منابع مشابه
Ascorbic acid augments colony spreading by reducing biofilm formation of methicillin resistant Staphylococcus aureus
Objective(s):Staphylococcus aureus is a Gram-positive pathogen, well known for its resistance andversatile lifestyle. Under unfavourable conditions, it adapts biofilm mode of growth. For staphylococcal biofilm formation, production of extracellular polymeric substances (EPS) is a pre-requisite, which is regulated by ica operon-encoded enzymes. This study was designed to know the impact of ascor...
متن کاملCell-Surface Phenol Soluble Modulins Regulate Staphylococcus aureus Colony Spreading
Staphylococcus aureus produces phenol-soluble modulins (PSMs), which are amphipathic small peptides with lytic activity against mammalian cells. We previously reported that PSMα1-4 stimulate S. aureus colony spreading, the phenomenon of S. aureus colony expansion on the surface of soft agar plates, whereas δ-toxin (Hld, PSMγ) inhibits colony-spreading activity. In this study, we revealed the un...
متن کاملModulation of Staphylococcus aureus spreading by water.
Staphylococcus aureus is known to spread rapidly and form giant colonies on the surface of soft agar and animal tissues by a process called colony spreading. So far, the mechanisms underlying spreading remain poorly understood. This study investigated the spreading phenomenon by culturing S. aureus and its mutant derivatives on Tryptic Soy Agarose (TSA) medium. We found that S. aureus extracts ...
متن کاملInhibition of Colony-spreading Activity of Staphylococcus Aureus by Secretion of Delta-hemolysin
Background: Staphylococcus aureus spreads on soft agar surfaces, a phenomenon called “colony-spreading”. Results: We purified delta-hemolysin from S. aureus culture supernatant as an inhibitor of colony-spreading, and its disrupted mutant had high colony-spreading ability. Conclusion: S. aureus negatively regulates colony-spreading by secreting delta-hemolysin. Significance: This is the first e...
متن کاملAscorbic acid augments colony spreading by reducing biofilm formation of methicillin-resistant Staphylococcus aureus
Objectives Staphylococcus aureus is a Gram-positive pathogen, well known for its resistance and versatile lifestyle. Under unfavourable conditions, it adapts biofilm mode of growth. For staphylococcal biofilm formation, production of extracellular polymeric substances (EPS) is a pre-requisite, which is regulated by ica operon-encoded enzymes. This study was designed to know the impact of ascorb...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 2007
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.01635-06